The aim of this study was to evaluate the safety and efficacy of the new prescription weight loss medication orlistat in patients with obesity. Methods
An open label, randomized, double-blind, placebo-controlled study was performed to evaluate the safety and efficacy of orlistat in patients with obesity who did not have a previous prescription for the prescription. Patients with a BMI of 30 kg/m2, body mass index (BMI) of 27 or more, were randomly assigned to receive either 120 mg or the new prescription orlistat (n=814) for a period of one year. The primary end point was the weight change from baseline, measured by the primary end point BMI, as well as the change in the HbA1c level and total cholesterol levels from baseline. There were significantly fewer weight gain for the orlistat group than the placebo group. The number of participants who lost more than 5% of their body weight was not significantly different in the two groups.
Overall, there were fewer patients in the orlistat group than in the placebo group (17.0% versus 13.6%, respectively;P=0.03). A significant increase in the HbA1c level was observed in the orlistat group, but no change in the weight loss was observed in the placebo group.
In conclusion, this study showed that the new prescription orlistat reduced the weight change from baseline from baseline (6.9% to 5.6% at 1 year), while no change in the weight loss was observed in the placebo group.
The new prescription orlistat reduced the weight change from baseline from baseline, but no change in the weight loss was observed in the placebo group. These data suggest that this new prescription orlistat is safe and effective in patients with obesity, and that it is a suitable option for patients who do not have a previous prescription for the prescription.
Citation:Ozumet-Yasimovic O, Yisimovic-Arya Y, Tarijan P, Kochen-Hirschrition A, Mounat-Arya M (2018) Randomized, double-blind, placebo-controlled study evaluating the efficacy and safety of orlistat (n=814) for the treatment of obesity in adults and adolescents. PLoS ONE 13(2): e0184861. https://doi.org/10.1371/journal.pone.0184861
Editor:Yazizadeh Haber, University of Texas Southwestern Medical Center, Dallas, TX, USA
Received:April 9, 2018;Accepted:April 25, 2018;Published:June 11, 2018
Copyright:© 2018 Ozumet-Yasimovic et al. This is an open access article distributed under the terms of the, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Data Availability:The data behind the results are available from the corresponding author in the.
Funding:The authors received no specific funding for this work.
Competing interests:The authors have declared that no competing interests exist.
Obesity is a growing global public health burden. The rising prevalence of obesity is projected to contribute to the global morbidity and mortality, and it is estimated that in the next decade, 5.3 million adults worldwide are overweight, and a third of them will be in the obese class of diabetes. Obesity is often a consequence of a physical in nature (i.e., lifestyle), as it has an indirect impact on the physical health of the body by increasing the risk of cardiovascular disease, and the development of type 2 diabetes.
Obesity has been associated with a range of health problems, including cardiovascular disease, type 2 diabetes, and a higher prevalence of obesity-related disorders, including metabolic syndrome and type 2 diabetes. The risk of these disorders is thought to be dependent on the extent and severity of the disease and the type of the underlying cause.
Obesity is a risk factor for various diseases, including type 2 diabetes, cardiovascular disease, and an increased risk of diabetes. The main risk factors for diabetes are obesity (i.e.
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This product is a Prescription Only Medicine (S4) and is sold by Healthylife Pharmacy, an independently owned and operated pharmacy business. This prescription product requires a valid Australian script.
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Healthylife Product InformationThis product is a Prescription Only Medicine (S4) in a 120mg strength (5 times the strength of a prescription strength) Xenical Orlistat (120mg). The main active ingredient is Orlistat. This medicine is also available as an herbal product (except for the high-fat product "Alli," which is not). Product shockingly, Healthylife has not released a product information sheet regarding this particular product. Healthylife does not recommend use by individuals under the age of 18 years. Product information is provided toousekimucky.com.au with payment through checkout. Product labels are provided in packs to reflect the number of prescriptions, the strength, the date of dispensing and the quantity of pills taken. Healthylife does not endorse or recommend the safety, efficacy or proper use of the product provided. Product packaging is provided for your information only. Please read product packaging and bear in mind if you purchase or have recently ordered this product.
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Healthylife Prescription StrengthThis medicine contains the active ingredient Orlistat. It is supplied by Healthylife Pharmacy, an independently owned and operated pharmacy business. If you have any questions about the use of this product, please contact your doctor or pharmacist.
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Healthylife provides a variety of storage options depending on your local area.
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Healthylife provides a variety of different storage options. This is a prescription only medicine. If you are experiencing symptoms of a PSA, please contact your doctor or a healthcare professional.p.a.
Orlistat 120mg is an antibiotic used to treat obesity and help with weight loss. Orlistat 120mg prevents your body from eating fat and stops the process from happening. It also prevents the release of some gas in your intestines. Weight loss by orlistat 120mg can be achieved in under an hour.
Orlistat 120mg is a prescription drug. You will need a prescription from a doctor to purchase and use this drug. Orlistat 120mg (Xenical/Alli) is a weight loss medication that contains orlistat 120mg. Be sure to take this drug in the morning with a glass of water.
How to use:
Take this drug by mouth with or without food. You can take this drug with or without food. Orlistat 120mg should be taken at least 30 minutes before or after a meal. Do not take more than one drug at a time. Orlistat 120mg will reduce the amount of fat in your diet. Be sure to take this drug in the dose and duration as advised by your doctor. Swallow the capsules whole. Do not chew, crush, or open the capsules. Orlistat 120mg can change the taste of your medication. You can add different foods and activities to your routine while you are taking this drug. Tell your doctor if you are using any of the following:
Be sure to talk to your doctor if you are using any other drugs while you are taking this drug. Some drugs can affect the way this drug works.
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Xenical, a prescription weight loss medication, is a prescription drug that is designed to treat obesity. It works by inhibiting the absorption of fats in the gut, leading to an increase in satiety and a reduction in calorie intake. Xenical works by targeting the absorption of dietary fat, which is a type of fat that is absorbed from the gastrointestinal tract. This leads to an increase in calorie intake and promotes weight loss. In addition, Xenical can help to regulate appetite and reduce food cravings, making it easier for people to maintain their weight. In addition, Xenical may help to reduce the amount of fat consumed during a meal. This can help to enhance the metabolism of fat in the body, leading to an increased body weight. In recent years, more and more studies have been conducted to explore the effects of Xenical on obesity. It is important to note that the benefits of Xenical should not be underestimated and should only be done under the guidance of a healthcare provider. This medication can be used to help people who have obesity, such as those with a BMI between 18.5 and 25.0, and those with a BMI of 30 or more. It is important to consult a healthcare provider before starting this medication, particularly if you have a history of heart disease, high blood pressure, liver or kidney disease, or are taking a weight loss medication such as Orlistat. It is also important to note that Xenical should only be used as part of a comprehensive treatment plan to achieve weight loss. It is crucial to follow the prescribed dosage and schedule and avoid taking it with a meal or a snack before eating. It is important to consult a healthcare professional if you have any concerns or questions about Xenical and its use. It is also important to weigh up the benefits of this medication with other weight loss treatments, such as diet and exercise. It is also important to understand that Xenical is a weight loss medication, and it may not be suitable for everyone.
Amino- orlistat is used to help lower blood pressure. It can be taken alone or in combination with other anti-obesity medicines, or a combination of the two.
The dosage of Orlistat depends on your age, weight, and medical history. The lowest recommended dose is one capsule taken with water or at bedtime.
Some common side effects of Orlistat include:
If you experience any severe or persistent side effects, stop taking Orlistat and contact your doctor immediately.
Orlistat should be used with caution in pregnant women and breastfeeding mothers.
Consult your doctor or pharmacist before using Orlistat if you are taking other medicines for obesity.
Orlistat may interact with some drugs. Tell your doctor about all the medicines you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements. Do not start or stop any medicine without your doctor’s prescription.
Store Orlistat in a tightly closed container at room temperature, away from heat, moisture, and direct light. Keep out of children’s reach.
ReferencesQ: How long does Orlistat take to work?A: Orlistat takes up to 3 to 4 weeks to work.
Q: How long does Orlistat work?A: Orlistat works quickly, typically within 1 to 2 hours.
Q: How long can Orlistat take to work?A: Orlistat can take up to 3 to 4 weeks to start working.
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